ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer by Ana García-García (17779885)

“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease, marked by a survival rate of only 12%. …”

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Kaplan-Meier survival analysis comparing patients admitted before or during the COVID-19 period. by Rajkumar Rajendram (22505442)

Detailed table of two-tailed Pearson correlation analysis results between different phenotypic data tested above and lectin microarray results. by Yiying Zhang (198443)

PEDV and PDCoV infection impairs the cilium. by Tenghan Zhuang (22238809)

“…Notably, infection by either porcine epidemic diarrhea virus (PEDV) or porcine deltacoronavirus (PDCoV) resulted in a significant decrease in both the percentage of cells with cilium and the average ciliary length across all three porcine cell lines (<i>C-D, F-G, and I-J</i>). …”

Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”

Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”

The effect of PCAIs on G-protein levels. by Matthew D. Gregory (19929096)

Thirty-day inpatient survival by admission serum sodium concentration: Kaplan-Meier analysis stratified by pre- and during-COVID-19 pandemic periods. by Rajkumar Rajendram (22505442)

Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation. by Hilary T. Brewis (11798006)

“…There was overlap found in all four groups: 1) genes that had increased mRNA expression and H2A.Z enrichment at their TSS in the HU-treated condition, 2) mRNA expression increased, while H2A.Z enrichment decreased, 3) mRNA expression decreased, while H2A.Z enrichment increased, and 4) genes where mRNA expression and H2A.Z enrichment at the TSS decreased after HU exposure. …”

Comparison of the particular blood cell parameters across the various murine treatment groups. by Maryam Banar (3220221)

PCAIs suppress 3D NCI-H23 cell invasion. by Matthew D. Gregory (19929096)

Profile of study locations and participants. by Hammed O. Mogaji (9421930)

“…Data analysis was conducted using R software version 4.3.2, with a 95% confidence interval.</p><p>Principal findings/conclusions</p><p>The parasitological data indicated a significant decline in the aggregated prevalence of STH across the three IUs. …”

Table 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.docx by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Table 1_Association between androgenetic alopecia and psychological well-being: a systematic review and meta-analysis.docx by Yuan Kong (110669)

“…Background<p>Androgenetic alopecia (AGA) is a prevalent chronic condition with health burden, yet its association with psychological well-being remains inconsistent. …”

Image 2_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx by Hailan Yan (18174379)

“…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. …”

Image 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif by Qiwang Mo (9091292)

“…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR_PDI = 0.85; 95% CI: 0.80–0.90; pooled HR_hPDI = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …”

The expression levels of tasiR-ARF3 and tasiR-ARF3 targets in empty vector (EV)-, p20-, p20 ^mAIM1 -, and p20 ^mAIM5 -infiltrated <i>Nicotiana benthamiana</... by Yongle Zhang (11355546)

Table 1_Efgartigimod combined with steroids as a fast-acting therapy for anti-SRP immune-mediated necrotizing myopathy.doc by Qiqi Peng (6560057)

“…</p>Results<p>Following one cycle of efgartigimod treatment (administered at a dosage of 10 mg/kg, once a week for a total of 4 injections in one period) in these three patients, CK values decreased by 79.30, 95.80, and 93.62%, respectively. …”