يعرض 7,241 - 7,260 نتائج من 18,496 نتيجة بحث عن 'significantly ((largest decrease) OR (((((greater decrease) OR (a decrease))) OR (mean decrease))))', وقت الاستعلام: 0.78s تنقيح النتائج
  1. 7241

    Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

    منشور في 2025
    "…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"
  2. 7242

    Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

    منشور في 2025
    "…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"
  3. 7243

    Data Sheet 1_Effect of a high dose atorvastatin as adjuvant therapy to mesalamine in attenuating inflammation and symptoms in patients with ulcerative colitis: a randomized control... حسب Sumaiah J. Alarfaj (12889115)

    منشور في 2025
    "…</p>Results<p>Compared to the placebo group (n = 24), the atorvastatin group (n = 23) exhibited a significant decrease in the level of IL-6 (p = 0.001), S1P (p = 0.0001), TNF-α (p = 0.003), NO (p = 0.0001), CRP (p = 0.015), ESR (p = 0.012), PMS (p = 0.013), and fecal calprotectin (p = 0.0003), and improved SF-36 (p = 0.006). …"
  4. 7244
  5. 7245

    Livestock–Crop–Mushroom (LCM) Circular System: An Eco-Friendly Approach for Enhancing Plant Performance and Mitigating Microbiological Risks حسب Dong Liu (115204)

    منشور في 2025
    "…Mushroom production using agroforestry biowaste is a great green cycling agriculture alternative. …"
  6. 7246
  7. 7247

    Data Sheet 1_A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia.docx حسب Stephen B. Simons (19931955)

    منشور في 2024
    "…Introduction<p>The normal transition to sleep is characterized by a reduction in higher frequency activity and an increase in lower frequency activity in frontal brain regions. …"
  8. 7248

    <sup>177</sup>Lu-Labeled Heterodimeric Agent with High Stability Targeting Neovascularization for Tumor Radioligand Therapy حسب Biao Yang (545048)

    منشور في 2025
    "…Radiopharmaceutical theranostics holds significant promise in tumor diagnosis and treatment, but suboptimal tumor uptake and retention remain a persistent limitation. …"
  9. 7249

    Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx حسب Li Zhang (8200)

    منشور في 2025
    "…</p>Conclusions<p>Results suggest that a daily positive work reflection intervention is a feasible and promising intervention for decreasing Chinese nurses' psychological distress. …"
  10. 7250

    Image 1_A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis.jpeg حسب Michael R. Kann (22070273)

    منشور في 2025
    "…Across studies, the primary risk of bias was due to confounding variables, resulting in a serious risk of bias in 12 studies (48.0%).</p>Discussion<p>Kyphoplasty provides comparable outcomes in thoracic and lumbar VCFs, with no clinically significant differences in pain relief or procedural effectiveness. …"
  11. 7251

    Table 1_A comparison of clinical outcomes following kyphoplasty for osteoporotic compression fractures of the thoracic and lumbar spine: a systematic review and meta-analysis.docx حسب Michael R. Kann (22070273)

    منشور في 2025
    "…Across studies, the primary risk of bias was due to confounding variables, resulting in a serious risk of bias in 12 studies (48.0%).</p>Discussion<p>Kyphoplasty provides comparable outcomes in thoracic and lumbar VCFs, with no clinically significant differences in pain relief or procedural effectiveness. …"
  12. 7252

    Catalytic CO<sub>2</sub> Capture Performance of a MEA-EAE-DEEA Trisolvent in a Hot Silicon Oil-Based Pilot Plant حسب Yu Li (183836)

    منشور في 2024
    "…To implement an energy-efficient combination of CO<sub>2</sub> capture technology, the pilot plant studies were conducted in preparation of commercialization of CCUS demonstration plants, during which a set of specific amine blends with various catalytic packing was employed. …"
  13. 7253

    Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study حسب Kazuaki Oyake (7481357)

    منشور في 2025
    "…These individuals demonstrated significantly greater orthostatic cardiac index increases (F<sub>(5,105)</sub> = 2.75, <i>p</i> = 0.023, partial η<sup>2</sup> = 0.126) and more pronounced orthostatic total peripheral resistance index decreases (F<sub>(5,105)</sub> = 4.19, <i>p</i> = 0.002, partial η<sup>2</sup> = 0.166) than those without orthostatic hypotension.…"
  14. 7254
  15. 7255
  16. 7256
  17. 7257
  18. 7258
  19. 7259
  20. 7260