Image 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Image 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Image 4_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Table 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Image 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel by Paras Wanjari (22259362)

“…The compounds demonstrated significant proton transport when combined with valinomycin, indicating transmembrane proton transport for <b>1a</b>–<b>c</b>. …”

AdipoRon increases AdipoR-dependent AM fungal killing and reverses inflammatory phenotype. by Sri Harshini Goli (20889928)

Alveolar macrophages from APN pathway-deficient mice exhibit an inflammatory phenotype. by Sri Harshini Goli (20889928)

Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…A subseries of these molecules displays cellular inhibition of Ras–Raf binding, as well as decreased phosphorylation of the downstream protein ERK, demonstrating that potent multivariant Ras inhibitors can be accessed from this novel pocket.…”

Relation between the MDA concentration levels in lung tissue and clinical parameters of the groups. by Mustafa Tuşat (21094179)

Melting curves. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Original blot and gel image data. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Transfection sequences. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Experimental data. by Jingyan Yang (7120994)

“…The silencing of OIP5-AS1 in I/R conditions resulted in a significant suppression of cell apoptosis, reduced cleavage of caspase-3, decreased Bax levels, and increased Bcl-2 levels. …”

Relation between the TGFβ1 concentration levels in lung tissue and clinical parameters of the groups. by Mustafa Tuşat (21094179)

Comparison of step rate, step length, stance time, and flight time between tasks in eight intervals from the start to the 40 m mark. by Shinnosuke Hase (20917896)

Relation between the <i>TGFβ1</i> expression levels in lung tissue and clinical parameters of the groups. by Mustafa Tuşat (21094179)

Supplementary Material for: The Association of Proteinuria Target Achievement Timing and Stability with Adverse Kidney Outcomes Among Patients with IgA Nephropathy: A Cohort Study by figshare admin karger (2628495)

“…We analyzed the association between those three metrics and the composite kidney outcome, which was defined as the first occurrence of either end-stage kidney disease (ESKD or a >50% decrease in eGFR from baseline. Results: In Part A, the primary outcome occurred in 166 (18.65%) patients. …”

Supplementary file 1_Effects of a personalized PERMA-based intervention on the mental health of junior high school students: a randomized clinical trial.docx by Lei Zhang (38117)

“…No significant changes were observed in coping styles, though slight improvements in positive coping tendency (from −0.02 to −0.13) and a slight decrease in negative coping tendency (from −0.02 to −0.01).…”

Table 1_Managing lorlatinib-induced weight gain through a structured exercise intervention in an ALK+ NSCLC patient: a case report.docx by Christian Ciurnelli (20548178)

“…Although the weight remained stable, body composition analysis, via bioimpedance and CT scan, revealed a decrease in fat tissue and an increase in muscle mass. …”