Data Sheet 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.docx حسب Maria Jordan (10265489)

"…Introduction<p>Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease with high mortality. …"

Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx حسب Maria Jordan (10265489)

"…Introduction<p>Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease with high mortality. …"

Table 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.xlsx حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Supplementary file 4_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Development of immediate release tablet formulations of lornoxicam with hot melt extrusion-based three-dimensional printing technology حسب Aysel Yilmaz (20478966)

"…</p> <p>Although the solubility of LRX increases with pH, disintegrating agents such as MCC II had a more significant effect on the dissolution of LRX than sodium bicarbonate, which was used as the alkalinizing pore-forming agent. …"

Data Sheet 1_ZBP1 senses Brucella abortus DNA triggering type I interferon signaling pathway and unfolded protein response activation.pdf حسب Marco Túlio R. Gomes (5363324)

"…The knockdown of STING by siRNA decreased the residual IFN-β signal elicited by B. abortus infection, demonstrating the presence of a redundant cytosolic DNA-sensing mechanism driving type I IFN production. …"

ZNF503-AS2 had predictive value for chemotherapy and immunotherapy in glioma. حسب Yibo Wu (788885)

"…<p>(A) Ranking of the most sensitive and most resistant drugs with ZNF503-AS2 expression. …"

Supplementary file 5_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Supplementary file 6_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Supplementary file 1_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Data Sheet 1_Self-esteem and peer pressure susceptibility mediating the link between maternal behavior and adolescent risk behaviors.pdf حسب Marija Milić (10895373)

"…Although parental influence decreases and peer influence increases during this time, parental behavior still plays a significant role. …"

Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure حسب Bambarendage P. U. Perera (20190175)

"…The Pb-exposed male brain exhibited increased <i>Taok3</i> expression (<i>p</i> < 0.05) and decreased DNA methylation (FDR < 0.01). The results demonstrate that perinatal Pb exposure stably influences longitudinal piRNA expression in a tissue- and sex-specific manner, potentially via DNA methylation-directed mechanisms.…"

Supplementary file 3_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Supplementary file 2_Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients.pdf حسب Yanling Wen (552195)

"…Furthermore, we observed that Tregs in COVID-19 patients exhibited weakened TCR clonotype expansion, and the suppression of HLA_DR⁺ Tregs with expanded TCR clonotypes in severe COVID-19 cases did not show a significant increase compared to asymptomatic and mild COVID-19 groups. …"

Table 1_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.docx حسب Man Zhao (314232)

"…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …"

Data Sheet 1_An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance.docx حسب Chenchen Zhang (324804)

"…</p>Conclusion<p>Increased P. vulgatus and B. fragilis, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.…"

Variance of the first 20 principal components from the essential dynamics analysis of the unbiased MD simulation of GumK in the membrane-bound state. حسب Davide Luciano (22822210)

"…The cumulative variance shows that the first few principal components account for a significant percentage of the total variance.…"

Table 3_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.docx حسب Jiaoli Xu (20871584)

"…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…"

Table 1_Antiepileptic drugs and foetal disorders: analysis of 20-year data from the pharmacovigilance center.docx حسب Zejun Ji (20787176)

"…Background<p>For women of childbearing age, the risks of uncontrolled epilepsy to the mother and fetus need to be balanced against the potential teratogenic effects of antiepileptic drugs (AEDs). The combined use of different types of AEDs has become a potential treatment option for the effective control of epileptic symptoms, while different studies present significant difference between the combined use of AEDs and foetal toxicity, which need a large comprehensive study to clarify the relation.…"

Image 3_Global, regional, and national epidemiology of congenital heart disease in children from 1990 to 2021.tif حسب Jiaoli Xu (20871584)

"…Background<p>Congenital heart disease (CHD) is a leading cause of morbidity and mortality in children globally, with significant variations in outcomes across different regions.…"