Data Sheet 1_Association of oxidative balance score with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease.docx by Yucui Lin (21598376)

“…Moreover, Higher OBS quartiles were linked to a decreased risk of cardiovascular mortality, while no significant reduction was observed in the lower quartiles [model 3: Q2, Q3, Q4: aHR (95CI%) = 0.96(0.77–1.19), 0.78 (0.63–0.97), 0.70 (0.53–0.93), respectively; P for trend = 0.003]. …”

Table1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease... by Juan Tang (437969)

“…Age effects across all countries and genders demonstrated an increasing trend over time, indicating age as a significant risk factor for IHD. Moreover, period and cohort effects in higher SDI countries exhibited a more rapid decline in both genders compared to lower SDI countries. …”

Causal associations between gut <i>Bifidobacteriaceae</i> and transplant failure: a Mendelian randomization study by Han Yan (126662)

“…</p> <p>Mendelian randomization studies have shown that a lower abundance of Bifidobacteriaceae in the gut could increase the risk of transplant failure.…”

Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf by Rafaella Oliveira dos Santos (21710366)

“…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …”

 'Plan-B':  Impact of changes in the global funding landscape for Hepatitis B clinical and research programmes by marion delphin (13249479)

“…Respondents were mostly researchers / academics (34%) and healthcare workers (32%), with lower representation from people with lived experience of HBV (10%) or representing civil society organizations (10%). …”

Datasheet1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of dis... by Juan Tang (437969)

“…Age effects across all countries and genders demonstrated an increasing trend over time, indicating age as a significant risk factor for IHD. Moreover, period and cohort effects in higher SDI countries exhibited a more rapid decline in both genders compared to lower SDI countries. …”

Data Sheet 1_The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol.pdf by Javier Chávez Cerda (20913026)

“…Results indicate that the stimulation significantly decreased the heart rate below baseline levels for standard VNS (−120.0 ± 69.1 bpm) and breathing-synchronized VNS (−84.9 ± 61.0 bpm), overcoming the heart rate increasing effect of PTZ infusion observed in the sham VNS (+79.2 ± 35.5 bpm), and there was no recovery during OFF periods. …”

Genetic prediction of the relationship between mitochondrial proteins and diabetic polyneuropathy risk: a Mendelian randomization study by Zixiao Wang (6078317)

“…</p> <p>COA3, NFU1, and SARS2 significantly affect DPN risk, with COA3 lowering and NFU1 and SARS2 increasing risk. …”

Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”

The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... by Mohammed A. Altowijri (22461945)

“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”

The number of male–male agonistic interactions in relation to females with maximal swelling. by Heungjin Ryu (10747673)

“…<b>(D)</b> Visualization of the interdependency between the number of males and females with maximal swelling on the male aggression rate (significant interaction in LM-2E) shows that when there were a greater number of males in the party, e.g., Mean + 1SD (9.6 males in D), the male aggression rate decreased as the number of females with maximal swelling increased. …”

Video 2_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Video 3_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

DataSheet1_Hypoglycemic activity of Garcinia mangostana L. extracts on diabetes rodent models: A systematic review and network meta-analysis.docx by Moragot Chatatikun (14682400)

“…Background<p>Diabetes mellitus is a significant global health issue, and alternative treatments from natural products like Garcinia mangostana L. …”

Video 1_Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study.mp4 by Vladimir Gabai (38129)

“…Improvement in CBPI was observed after 2–4 weeks of treatment, whereas after 5–6 weeks of the treatment the parameters reached the plateau. After 10 weeks mean PSS score after the treatment decreased from 5.25 to 3.25, PIS score - from 7.0 to 3.27, and number of dogs with excellent and good QoL due to treatment increased from 1 to 12. …”

Data_Sheet_1_The association between Geriatric Nutritional Risk Index and KSD disease: results from National Health and Nutrition Examination Survey 2007–2018.ZIP by Zhicheng Tang (7010534)

“…</p>Conclusion<p>The study underscores a significant, albeit nonlinear, association between elevated GNRI levels and decreased KSD prevalence. …”

Data_Sheet_1_The association between Geriatric Nutritional Risk Index and KSD disease: results from National Health and Nutrition Examination Survey 2007–2018.ZIP by Zhicheng Tang (7010534)

“…</p>Conclusion<p>The study underscores a significant, albeit nonlinear, association between elevated GNRI levels and decreased KSD prevalence. …”

DataSheet1_Updated evidence of the Naoshuantong capsule against ischemic stroke: a systematic review and meta-analysis of randomized controlled trials.docx by Cuilin Que (19743256)

“…Background<p>Stroke is a serious health issue that can result in death or disability, leading to a significant economic strain on society and families. …”