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4481
Figure 2 from Loss of Sorting Nexin 10 Accelerates KRAS-Induced Pancreatic Tumorigenesis
Published 2025“…<p>OE of SNX10 decreased cell proliferation in AsPC1 and HPAF-II PDAC cell lines. …”
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4482
Image 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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4483
Data Sheet 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through a...
Published 2025“…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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4484
Data_Sheet_1_Syncing the brain’s networks: dynamic functional connectivity shifts from temporal interference.pdf
Published 2024“…</p>Results<p>For CV of dFC, significant main effects of stimulation type (P = 0.004) and time (P < 0.001) were observed. …”
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4485
Table 1_Evaluation of IVIM and FACT imaging for early detection of rotator cuff muscle degeneration and physiotherapy exercise effects.docx
Published 2025“…Additionally, the change in D* and f correlated with CS, ASES scores and VAS scores respectively. FF showed a decreasing trend but lacking significance (p > 0.05).…”
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4486
Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati...
Published 2025“…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …”
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4487
PbCBP-O is required for efficient midgut traversal.
Published 2025“…In all relevant panels, statistical significance is indicated as: ns = not significant, ** = p < 0.01, *** = p < 0.001 and **** = p < 0.0001.…”
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4488
Image 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati...
Published 2025“…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …”
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4489
Table1_Around the clock: unveiling giraffe rest-activity rhythms and social dynamics.docx
Published 2024“…The presence of a male giraffe during one intervention phase significantly altered diurnal activity patterns, increasing standing behaviors and decreasing feeding time. …”
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4490
Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf
Published 2024“…Observational study subgroup showed decreased short-term mortality, long-term mortality, and CPC 1–2 at discharge, unlike RCT subgroup. …”
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4491
Table 5_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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4492
Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc
Published 2025“…Furthermore, both SDUY429 and SDUY436 remarkably suppressed the migration and invasion of MDA-MB-231 cells by downregulating the protein kinase B (AKT)/glycogen synthase kinase-3 beta (GSK3β)/β-catenin signaling pathway. The observed reduction in phospho-AKT-Ser473 (pAKT<sup>S473</sup>) expression resulted in the decreased levels of phospho-GSK3β-Ser9 (pGSK3β<sup>S9</sup>), thereby limiting the nuclear localization of β-catenin, which led to the inhibition of cell migration and invasion. …”
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4493
Table 4_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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4494
Supplementary file 1_Biodegradation potential of Gordonia spp. on polypropylene and polystyrene: enhanced degradation through pretreatment.docx
Published 2025“…</p>Results<p>Notably, Gordonia polyisoprenivorans B253 demonstrated remarkable degradation capabilities, as evidenced by: (1) characteristic chemical modifications including hydroxyl group formation (3,280 cm<sup>−1</sup>), carbon-carbon double bond generation (1,640 cm<sup>−1</sup>), and ether group appearance (1,100 cm<sup>−1</sup>) in ATR-FTIR spectra; (2) pronounced surface erosion patterns observed via SEM; and (3) significant mass reduction (1.927% ± 0.038% of PS) compared to controls. …”
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4495
Table 2_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”
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4496
Data Sheet 1_Genome-wide association analysis of grain iron and zinc in rice grown under agroclimatic sites with contrasting soil iron status.pdf
Published 2025“…Additionally, the response of these lines to Fe toxicity was assessed at one location.</p>Results<p>Significant phenotypic variation for both traits was observed. …”
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4497
Table 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx
Published 2025“…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I<sup>2</sup> = 99%, p < 0.001) was observed across studies.…”
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4498
Table 1_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx
Published 2025“…</p>Results<p>New reference values for older adults were established. Significant differences (p < 0.001) in R/H and phase angle were observed when older adults were grouped by age categories, while R/H, Xc/H, and phase angle showed significant differences among ALSM/H<sup>2</sup> tertiles. …”
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4499
Data Sheet 1_Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial.docx
Published 2025“…Exploratory endpoint analyses revealed significant decreases in pro-inflammatory cytokines, degranulating CD8<sup>+</sup> T lymphocytes, and NK cells in the treatment group. …”
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4500
Table 3_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x...
Published 2025“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”