Data Sheet 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.zip حسب Junxian Hu (8158044)

"…CRT also exhibits distinct roles depending on its subcellular localization. In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …"

Table2_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Table3_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.XLSX حسب Na Wang (193263)

"…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …"

Supplementary Material for: Global, regional, and national epidemiology of Idiopathic Childhood Epilepsy from 1990 to 2021 حسب figshare admin karger (2628495)

"…Regionally, Southern Latin America saw the largest increase in incidence (EAPC, 0.49), and Eastern Europe observed the most significant mortality decrease (EAPC, -4.65). Ecuador reported the highest incidence rate, Tajikistan the highest mortality, and Zambia the highest DALYs in 2021. …"

Supplementary material Figure S3 حسب Alireza Mani (3341171)

"…For the PD networks (left column), the nodes represent the physiological variables, the edges show significant correlations (p≤Bonferroni-adjusted p-value) between the two nodes, and the edge labels display the mean PD values for no deterioration and deterioration groups along the significantly correlated variable pair axes. …"

Immunoblots analysis of mitophagy-related protein expression. حسب Michael O. Isei (20500908)

"…Densitometry quantification of the respective mitophagy receptors show that FKBP8 expression was significantly reduced in cells expressing EC and EM compared to T4 <b>(E)</b>, while BNIP3 and FUNDC1 receptor levels decreased significantly in all groups <b>(F, G)</b>. …"

Table 1_Gamma knife radiosurgery for cerebral cavernous malformations: biologically effective dose predicts therapeutic outcomes.docx حسب Xiaoman Shi (12587770)

"…</p>Conclusion<p>GKRS significantly reduced hemorrhage risk and promoted lesion regression in CCMs. …"

Table 2_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx حسب Wenjing Chang (8334480)

"…</p>Results<p>The overall mean adherence rate was 92%, with long-acting GH formulations associated with significantly higher adherence than daily GH injections (94% vs. 91%, p < 0.001). …"

Supplementary material Figure S2 حسب Alireza Mani (3341171)

"…For the PD networks (left column), the nodes represent the physiological variables, the edges show significant correlations (p ≤ Bonferroni-adjusted p-value) between the two nodes, and the edge labels display the mean PD values for survivors and non-survivor groups along the significantly correlated variable pair axes. …"

Table 1_Adherence to recombinant human growth hormone therapy in children: influencing factors and clinical implications.xlsx حسب Wenjing Chang (8334480)

"…</p>Results<p>The overall mean adherence rate was 92%, with long-acting GH formulations associated with significantly higher adherence than daily GH injections (94% vs. 91%, p < 0.001). …"

Supplementary file 1_Clinical utility of the PBAC score in quantifying treatment response to hysteroscopy: a retrospective observational study.docx حسب Ömer Faruk Öz (22702202)

"…Data were analyzed using SPSS version 26, and p < 0.05 was considered statistically significant.</p>Results<p>Of the 327 patients included in the study, 91.1% had a baseline PBAC score ≥100, which significantly decreased following hysteroscopy (mean reduction: 393 points; p < .001). …"

Table 1_Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study.docx حسب Sam Salek (5800727)

"…Background<p>Disease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.…"

Image5_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Image3_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Table1_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.docx حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Image1_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Image2_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Data Sheet 1_DYRK1A roles in human neural progenitors.docx حسب Jeremie Courraud (20871932)

"…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …"

Table2_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.docx حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Image4_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"