Datasheet2_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Table 1_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.docx by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Data Sheet 1_Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function.docx by Amy K. Stark (20470996)

“…</p>Methods<p>Based on the previously characterized proinflammatory roles of prostanoid signaling in DR, we assayed the distinct prostanoid signaling mechanisms regulating inner and outer blood-retina barrier function using in vitro methods involving monoculture of primary human cells.…”

Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx by Shenghua Lu (20762612)

“…Regarding neurological function, the BCP combination group significantly increased the Glasgow Coma Scale score (MD = 1.86, 95% CI 1.17 to 2.56, p < 0.00001) and decreased the National Institutes of Health Stroke Scale score (MD = −2.17, 95% CI −3.35 to −0.99, p = 0.0003). …”

Table_1_Outcomes of retroperitoneal fibrosis-related hydronephrosis and its risk factors for poor prognosis: a multi-center retrospective cohort study in Chinese patients.DOCX by figshare admin frontiersin (4545187)

“…They were followed up until death or September 2021, whichever came first.</p>Results<p>The mean age at diagnosis was 58.83 ± 12.13 years, and 80 patients (69.57%) were men. …”

Image 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 6_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 4_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 2_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 5_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Table 3_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

Image 1_Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression... by Yifeng Zhang (521454)

“…Finally, the target genes were validated in AS model using Ldlr^−/− mice.</p>Results<p>We found that the proportion of Tregs significantly decreased, and Th2 cells showed a significant increase in atherosclerotic plaque compared to that in non-plaque arterial tissues. …”

DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx by Teng Qi (278739)

“…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. High GLI1 expression indicated better survival outcomes and was correlated with the age and stage of BRCA patients. …”

Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Bl... by figshare admin karger (2628495)

“…Results: Both groups showed a significant decrease in the percentage of multiple-step responses (p=0.013) and a shorter total recovery time to recover balance (p=0.006). …”

Data Sheet 1_Impact of primary production and net ecosystem metabolism on carbon and nutrient cycling at the land-sea interface.docx by Louise C. V. Rewrie (21016172)

“…When turbidity decreased in late spring (May), we observed elevated GPP rates, and highest GPP rates in summer (June-August), with seasonal averages of 613 ± 89 mg C m^-2 d^-1 in 2020 and 558 ± 77 mg C m^-2 d^-1 in 2021. …”

Data Sheet 1_Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study.pdf by Rebecca Lyng Holm (20620406)

“…</p>Results<p>We detected insulin in all 240 samples, with an average concentration of 12.3 (SD 8.8) μIU/mL (range 3.2–57.2 μIU/mL). …”

Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia by Andrew P. Lane (20367704)

“…<p>Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP) and significantly impacts health-related quality-of-life. …”

Supplementary file 1_Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY2.docx by Zhiqi Yang (2692909)

“…In the presence of nifedipine, LEFTY2 did not further modify trypsin induced increase of [Ca²⁺]_i. LEFTY2 significantly decreased levels of L-type Ca²⁺ channel.…”