Table 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Image 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Table 5_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Table 1_Disparities in the burden of tuberculosis associated with urbanization across 178 countries and territories: an observational study.docx by Yaping Wang (289641)

“…However, there is limited quantitative evidence on the impact of urbanization on TB burden. We aimed to assess the relationship between urbanization and the global TB burden.…”

Telomere-to-telomere genome of <i>Phoebe chekiangensis</i> reveals age-dependent CHG hypomethylation promoting floral transition via MADS-box gene activation by Qinglin Sun (17811556)

“…Their ectopic expression in Arabidopsis significantly accelerated flowering. Whole-genome bisulfite sequencing revealed an age-related decrease in CHG methylation, particularly at the PcMADS19.1 locus. …”

Data Sheet 1_Direct and indirect effects of land use on microbiomes of trap-nesting solitary bee larvae and nests.docx by Birte Peters (12323923)

“…</p>Results<p>As expected, we observed significant shifts in the bacterial composition and diversity of bees and their nests across varying degrees of land use intensity, differing in management types and the availability of flowers. …”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

Data from "A Historical Misstep: Niche Shift to Specialisation Is Pushing Insular Ginger Towards an Evolutionary Dead End" by Min-Wei Chai (15899033)

“…<i>Z. shuanglongense</i>, as the specialist, despite an initial increase during the Last Glacial Maximum (~22 Kya), has been subjected to a long-term decrease in effective population size (<i>Ne</i>), while <i>Z. pleiostachyum</i> is on the contrary increasing, leading to a significantly larger current <i>Ne</i>. …”

Data Sheet 1_Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study.pdf by Kaiwen Wang (838527)

“…</p>Results<p>There was no causal relationship between sex hormones and IBD in women (P > 0.05), and there was a causal and positive correlation between SHBG and testosterone and IBD in men.The OR for SHBG was 1.22 (95% CI: 1.09-1.37, P = 0.0004), and for testosterone was 1.20 (95% CI: 1.04-1.39, P = 0.0145).IBD did not significantly interact with female sex hormones but resulted in a decrease in SHBG (OR = 1.02, 95% CI: 1.00-1.04, P = 0.0195) and testosterone (OR = 1.01, 95% CI: 1.00 -1.02, P = 0.0200) in men.…”

Data Sheet 1_Assessment of heat-killed E. coli expressing Chikungunya virus E2 protein as a candidate vaccine for dual protection against Chikungunya virus and E. coli.docx by Surajit Patra (18400578)

“…Similarly, the vaccine formulation also elicited a significantly higher IgG immune response against E. coli. …”

Data Sheet 1_Body position influence on cerebrospinal fluid volume redistribution inside the cranial and spinal CSF compartments.pdf by I. Strbačko (20633240)

“…</p>Results<p>Volumes of brain and spinal cord tissue did not change during body position changes. Significant CSF volume (ml) changes occur inside the spinal space in the tested body positions, primarily in the lumbosacral segment (H-UP – 38.1 ± 7.0; H – 34.4 ± 6.5; B-UP – 28.7 ± 6.5), while at the same time no significant CSF volume changes have been observed inside the cranium in two tested positions (H and B-UP) in which it was possible to measure intracranial CSF volume changes or if we sum up cervical and cranial CSF volumes in those positions.…”

DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

<b>Artificial cilia for </b><b>360° </b><b>direction-sensitive acoustic</b><b> sensing</b><b> through additive micromanufacturing</b> by Yikang Li (19213120)

“…The response of the artificial cilia at resonance is significantly enhanced, while the resonance frequencies decrease with increasing length. …”

DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

Table_1_Does disaster resettlement reshape household livelihood adaptive capacity in rural China?.xlsx by Tiejun Zhao (230582)

“…The Chinese government has tried to use disaster resettlement to address ecological protection and social development problems, and it plays a crucial role in China’s development programs. We provide evidence that disaster resettlement leads to a decrease, rather than an increase, in HLAC. …”

Data Sheet 1_Discovery of biological markers for schizophrenia based on metabolomics: a systematic review.zip by Gaolei Yao (18253633)

“…Introduction and methods<p>To discover biomarkers for schizophrenia (SCZ) at the metabolomics level, we registered this systematic review (CRD42024572133 (https://www.crd.york.ac.uk/PROSPERO/home)) including 56 qualified articles, and we identified the characteristics of metabolites, metabolite combinations, and metabolic pathways associated with SCZ.…”

Supplementary Material for: A Novel Case of Ischemic Colitis in the Setting of Kratom Use: A Case Report by figshare admin karger (2628495)

“…There are no approved medical indications for kratom use, but several mice studies and a cross-sectional study in humans have demonstrated that kratom use can significantly decrease withdrawal symptoms among opioid users. …”

Datasheet1_Analysis of blood metabolite characteristics at birth in preterm infants with bronchopulmonary dysplasia: an observational cohort study.pdf by Yanping Guo (2467576)

“…To control for GA differences, we conducted a subgroup analysis. In the GA 24⁺⁴–27⁺⁶ weeks subgroup, we observed a significant decrease in histidine levels and the ornithine/citrulline ratio in the BPD group. …”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

PRISMAS flowchart of the screening process. by Xianghong Hu (17966261)

“…</p><p>Conclusions</p><p>The available evidence indicates that preoperative PENG block can significantly decrease opioid consumption and pain early after hip surgery, and it may also promote early functional rehabilitation. …”