First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Table 1_Molecular hybridization modification improves the stability and immunomodulatory activity of TP5 peptide.docx by Junyong Wang (3807964)

“…The half-life of YTP in plasma is significantly longer than that of YW12D and TP5. YTP also displays an improved ability to protect the host from CTX-induced weight loss and thymus and spleen indices decrease than YW12D and TP5. …”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

Paddy yield comparison in DSR and PTR. by Shiladitya Dey (18597784)

“…Both PSM and ESR-based results show that DSR adoption may increase paddy yield in Uttar Pradesh, Andhra Pradesh, and Telangana and decrease it in Madhya Pradesh, but net income from paddy farming increased significantly (Rs5009/acre to 8134 based on different locations) in all four states. …”

Supplementary file 1_Distance and orientation of hydrophones influence the received soundscape in shallow coral reefs.docx by Juan Carlos Azofeifa-Solano (10983207)

“…Using a spatial array of hydrophones, we recorded sound at different distances (1 m, 2 m, 5 m) and orientations (vertical vs. horizontal) from a shallow coral reef.…”

Comparative analysis of PSM outcomes. by Shiladitya Dey (18597784)

“…Both PSM and ESR-based results show that DSR adoption may increase paddy yield in Uttar Pradesh, Andhra Pradesh, and Telangana and decrease it in Madhya Pradesh, but net income from paddy farming increased significantly (Rs5009/acre to 8134 based on different locations) in all four states. …”

ALKBH5 induces macrophage activation to promote renal fibrosis via Retnla by Long Zheng (694761)

“…Macrophage-specific ALKBH5 knockout could significantly alleviate renal fibrosis in UUO mice and decrease the infiltration of macrophages in the kidneys. …”

Data Sheet 1_Global trends and future predictions of gastrointestinal ulcers in youth.pdf by Kun He (178646)

“…The ARIMA model, identified as the most accurate prediction model, suggests that by 2050, the burden of gastrointestinal ulcers in this age group will significantly decrease compared to 2019. Over the next 30 years, the global number of incident cases will initially rise before stabilizing, prevalent cases will fluctuate, and both DALYs and deaths will decline. …”

Supplementary Material for: The Impact of Changes in Fasting Plasma Glucose Before and After Heart Failure Diagnosis on All-Cause Mortality by figshare admin karger (2628495)

“…FPG levels were measured before and after HF diagnosis and categorized into five groups: significant decrease (Q1), mild decrease (Q2), stable (Q3), mild increase (Q4), and significant increase (Q5). …”

Supplementary Material for: Effects of a Sugar-Sweetened Beverages Tax on Caries in Italy: a Modelling Study. by figshare admin karger (2628495)

“…The projected 2025–2034 implementation estimated to decrease the DMFT by 0.07, save €38.6 million, and €31,933 per QALY gained. …”

Supplementary Material for: Patients with Opioid Use Disorder Choosing Treatment with Extended-Release Naltrexone: A 6-Months Naturalistic Study by Brenna I.H. (19773549)

“…The majority of the MITT population (84; 60.9%) completed 24 weeks of treatment in the study. There was a significant decrease in the overall use of opioids (p<0.001) and the use of alcohol and other illicit substances was low. …”

Image 4_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg by Shunji Yamada (5543327)

“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”

Image 1_Neuropeptide Y neurons in the basolateral amygdala project to the nucleus accumbens and stimulate high-fat intake.jpeg by Shunji Yamada (5543327)

“…The optogenetic inactivation of BLA NPY neurons projecting to the NAc caused a significant decrease in HFD intake for a 1-h period, while optogenetic activation of these neurons induced the opposite effect. …”

<i>E²GO</i>: Free Your Hands for Smartphone Interaction by Shaoming Yan (21339553)

“…Before the interaction, an anti-jitter gaze estimation method was exploited to stabilize human eye fixation and predict accurate and stable human gaze positions on smartphone screens to further explore refined time-dependent eye-gaze interactions. We also integrated an event-triggering mechanism in <math><mrow><mrow><mi>E</mi></mrow><mn>2</mn>GO</mrow></math> to significantly decrease its power consumption to deploy on smartphones. …”