DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

Table_1_Does disaster resettlement reshape household livelihood adaptive capacity in rural China?.xlsx by Tiejun Zhao (230582)

“…The Chinese government has tried to use disaster resettlement to address ecological protection and social development problems, and it plays a crucial role in China’s development programs. We provide evidence that disaster resettlement leads to a decrease, rather than an increase, in HLAC. …”

Data Sheet 1_Discovery of biological markers for schizophrenia based on metabolomics: a systematic review.zip by Gaolei Yao (18253633)

“…Introduction and methods<p>To discover biomarkers for schizophrenia (SCZ) at the metabolomics level, we registered this systematic review (CRD42024572133 (https://www.crd.york.ac.uk/PROSPERO/home)) including 56 qualified articles, and we identified the characteristics of metabolites, metabolite combinations, and metabolic pathways associated with SCZ.…”

Supplementary Material for: A Novel Case of Ischemic Colitis in the Setting of Kratom Use: A Case Report by figshare admin karger (2628495)

“…There are no approved medical indications for kratom use, but several mice studies and a cross-sectional study in humans have demonstrated that kratom use can significantly decrease withdrawal symptoms among opioid users. …”

Datasheet1_Analysis of blood metabolite characteristics at birth in preterm infants with bronchopulmonary dysplasia: an observational cohort study.pdf by Yanping Guo (2467576)

“…To control for GA differences, we conducted a subgroup analysis. In the GA 24⁺⁴–27⁺⁶ weeks subgroup, we observed a significant decrease in histidine levels and the ornithine/citrulline ratio in the BPD group. …”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…Levels of autophagy were monitored using a double-labeled lentivirus (mRFP-GFP-LC3) and electron microscopy, and western blot analysis was used to estimate the levels of autophagy-related proteins and FOXO1 in the two cell models after co-treatment with lipopolysaccharide (LPS) and siRNA against FOXO1.</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

PRISMAS flowchart of the screening process. by Xianghong Hu (17966261)

“…</p><p>Conclusions</p><p>The available evidence indicates that preoperative PENG block can significantly decrease opioid consumption and pain early after hip surgery, and it may also promote early functional rehabilitation. …”

Data Sheet 1_Determining the influence of tree age on tea quality-related metabolites in Camellia tachangensis var. remotiserrata by integrating metabolomic and transcriptomic anal... by Zhuorong Shi (22589729)

“…Levels of relatively abundant phenolic acids (e.g., ferulic acid-4-O-glucoside, p-coumaric acid-4-O-glucoside) and flavonoids (e.g., luteolin-3’-O-glucoside, apigenin-4’-O-glucoside) decrease, while catechin content increases significantly, particularly epigallocatechin gallate derivatives. …”

Data Sheet 1_Combination of Sodium Butyrate and Immunotherapy in Glioma: regulation of immunologically hot and cold tumors via gut microbiota and metabolites.docx by Sui Li (8872481)

“…MRI imaging, Immunohistochemistry, and Immune cell flow cytometry were used to investigate the therapeutic effects of combined sodium butyrate and PD-1 inhibitor treatment on glioma-bearing mice.</p>Results<p>We discovered that deacetylation-associated gene expression is significantly increased in glioma patients and affects patient survival time. …”

Data Sheet 1_New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis.docx by Ekaterina Semina (12152564)

“…The study represents the first attempt to explore the role of T-cadherin in COVID-19 pathogenesis as well as its implications in pulmonary fibrosis and endothelial dysfunction. First, we revealed a significant decrease in T-cadherin expression in post-mortem lung samples from COVID-19 patients. …”

Table 1_Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies.docx by Francesco Di Pierro (3454346)

“…In Cohort 3, QP led to a 13.7% decrease in uric acid and a 20.8% reduction in triglycerides (p < 0.01), with no significant uric acid changes in the BM-treated group. …”

S1 Raw data - by Yongle Du (3992198)

“…Through integrating metabonomics and network pharmacology, we aimed to predict the anti-myopic targets and active ingredients of ZJP. …”

Supplementary Material for: The effect of LDL receptor–related protein–1 on acute kidney injury and renal tubular epithelial triglyceride accumulation by figshare admin karger (2628495)

“…The effects of VLDL and LRP1 silencing on triglyceride levels, cell viability, and apoptosis in HK-2 cells were observed. Results: We observed significant TG accumulation in renal tissue during IRI-AKI, accompanied by upregulation of LRP1 in renal tubular epithelial cells. …”

DataSheet1_Genome-wide association analysis and genomic prediction of salt tolerance trait in soybean germplasm.xlsx by Rongqing Xu (9504492)

“…Employing four distinct models—we performed a genome-wide association study (GWAS) using four models, including MLM, MLMM, FarmCPU, and BLINK in GAPIT 3, we conducted a Genome-Wide Association Study (GWAS) to identify single nucleotide polymorphism (SNP) associated with salt tolerance in soybean. …”

Data Sheet 1_Unveiling the effects of land use and intra-seasonal variation on bee and plant diversity and their ecological interactions in vegetation surrounding coffee plantation... by Quebin Bosbely Casiá-Ajché (14234267)

“…<p>Land use, local management, and seasonal variation significantly impact the ecological dynamics of bee–plant communities and their ecological interactions. …”

Data Sheet 1_The role of statins in dementia or Alzheimer’s disease incidence: a systematic review and meta-analysis of cohort studies.docx by Ye Du (4067569)

“…</p>Results<p>We included forty-two studies comprising 6,325,740 patients. …”

Primer sequences for target genes. by Yongle Du (3992198)

“…Through integrating metabonomics and network pharmacology, we aimed to predict the anti-myopic targets and active ingredients of ZJP. …”

Supplementary Material for: The effectiveness of Long-Term Continuation of Atezolizumab Plus Bevacizumab In Patients Who Receiving Systemic Chemotherapy For Advanced Hepatocellular... by figshare admin karger (2628495)

“…Group-L had significantly better overall survival (OS) than Group-S (not reached vs. 18 months, P = 0.008). …”

Data Sheet 1_Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.pdf by Tao Jiang (28401)

“…Background<p>The clinical application of recombinant tissue plasminogen activator (rt-PA) is significantly constrained by hemorrhagic transformation (HT), a common and severe complication following thrombolysis for ischemic stroke. …”

Supplementary Material for: Efficacy of team‑based collaborative care for distressed patients in secondary prevention of chronic coronary heart disease: Results from the multicente... by figshare admin karger (2628495)

“…Further, TeamCare led to a significantly greater decrease in depression (d=-0.329), anxiety (d=-0.300), perceived stress (d=-0.233), and medical risk score (d=-0.235). …”