Activity of female and male <i>M. marinus</i> (left column) and <i>G. pulex</i> (right column). by Charlotte N. Underwood (5043110)

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Average activity profiles (columns 1 & 3) and double-plotted actograms (col. 2 & 4) of <i>G. pulex.</i> by Charlotte N. Underwood (5043110)

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Behavioural parameters of <i>Marinogammarus marinus</i> and <i>Gammarus pulex</i> activity under varying light/dark cycles. by Charlotte N. Underwood (5043110)

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Average activity profiles (columns 1 & 3) and double-plotted actograms (col. 2 & 4) of <i>M. marinus.</i> by Charlotte N. Underwood (5043110)

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Locomotor activity of <i>Marinogammarus marinus</i> (left column) and <i>Gammarus pulex</i> (right column). by Charlotte N. Underwood (5043110)

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Light conditions for behavioural assays. Day phase length included the three-hour transitions at lights on/off, except under constant conditions (LL and DD). by Charlotte N. Underwood (5043110)

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Gardner-Altman plots showing changes from pre- to post-intervention. Physical performance (SPPB) but not handgrip strength, increases after creatine supplementation. by Waldo Bernales-Delmon (21865010)

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PRISMA flow diagram of study selection. by Masoud Rahmati (16665456)

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General characteristics of included studies. by Masoud Rahmati (16665456)

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Characteristics of individual studies. by Masoud Rahmati (16665456)

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Effects of compound 4f on neuroinflammation in mice with KA-induced neurodegeneration. by Naoto Arimura (416442)

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Top 20 IPA pathways of 2405 genes downregulated following KA treatment with a <i>P</i>-value of < 0.05. by Naoto Arimura (416442)

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All data in the manuscript and supporting information. by Naoto Arimura (416442)

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The effects of cannabinoid receptor antagonists against neuroprotective effects of compound 4f in KA-treated mice. by Naoto Arimura (416442)

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Representative image data in Fig 5. by Naoto Arimura (416442)

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Pharmacokinetics and pharmacodynamics of compound 4f in mice. by Naoto Arimura (416442)

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Effects of compound 4f on cognitive function in mice with KA-induced neurodegeneration. by Naoto Arimura (416442)

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Top 20 Ingenuity Pathway Analysis (IPA) pathways of 3382 genes upregulated following KA treatment with a <i>P</i>-value of < 0.05. by Naoto Arimura (416442)

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Effects of compound 4f on neuronal cell loss in mice with KA-induced neurodegeneration. by Naoto Arimura (416442)

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Top 20 IPA pathways of 1131 genes downregulated by compound 4f among genes upregulated following KA treatment with a <i>P</i>-value of < 0.05. by Naoto Arimura (416442)

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