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significantly impairs » significantly impacts (Expand Search), significantly impact (Expand Search), significantly improves (Expand Search)
decrease » decreased (Expand Search), increase (Expand Search)
significantly impairs » significantly impacts (Expand Search), significantly impact (Expand Search), significantly improves (Expand Search)
decrease » decreased (Expand Search), increase (Expand Search)
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1261
Functional assays of neurotoxicity testing of α-terpineol in Wistar rats
Published 2025“…The research found that exposure to α- terpineol led to several adverse effects, such as reduced body weight, impaired motor coordination, and significant declines in sperm parameters and testosterone levels. …”
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1262
Supplementary Material for: Fibrillin-1 deficiency perturbs aortic cholinergic relaxation and adrenergic contraction in a mouse model of early onset progressively severe Marfan syn...
Published 2025“…Results: Isometric force measurements of aortic rings from 16-day-old male Fbn1mgR/mgR mice revealed a significant reduction in acetylcholine (ACh)-induced relaxation and increased phenylephrine (PE)-promoted contractility, associated with abnormally low eNOSSer1177 phosphorylation, decreased NO production and augmented superoxide levels. …”
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1263
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
Published 2024“…Mechanistically, molecular interaction networks of Ingenuity Pathway Analysis identified a downregulated molecule, KIF5A (kinesin family member 5A), as a key target in TMT-impaired autophagic flux. TMT decreased KIF5A protein expression, disrupted the interaction between KIF5A and lysosome, and impaired lysosomal axonal transport. …”
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1264
Table 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.xlsx
Published 2025“…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …”
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1265
Image 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.tif
Published 2025“…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …”
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1266
Supplementary Material for: Pharmacokinetic Properties of Dapagliflozin in Patients with Stage 4 Chronic Kidney Disease
Published 2025“…In the multiple-dose group, UACR decreased by 21% and 24-hour urinary protein decreased by 23% from baseline to 24 hours after the last dose. …”
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1267
Table 1_Unveiling neuroimmunology profile of immunological non-responders in HIV: a multimodal MRI approach.docx
Published 2024“…Furthermore, INRs exhibited significant alterations in functional connectivity in the temporal and occipital gyrus. …”
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1268
Exploring the effects of COVID-19 on verbal memory function in schizophrenia: Multiple case study and brief literature review
Published 2024“…<p>Individuals recovering from COVID-19 may experience persistent impairment in verbal memory performance, potentially due to illness-related hippocampal injury. …”
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1269
qorA associated data
Published 2025“…Notably, the <i>qorA</i> mutant exhibited impaired survival against neutrophil killing as well as reduced viability in human blood, plasma, and during mouse bloodstream infections, along with a significant decline in its anti-phagocytic capability. …”
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1270
Data Sheet 1_The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.pdf
Published 2025“…Furthermore, we also found significant associations between this variant and IGI, corrected insulin response (CIR), and DIo (All P < 0.001) in female individuals whose waist-to-hip ratio (WHR) is greater than 0.85, with considerable heterogeneity (P<sub>het</sub> = 0.009, 0.030, and 0.049, respectively) to male participants in the NGT individuals, but not in the impaired fasting glucose (IFG)/impaired glucose tolerance (IGT) individuals. …”
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1271
Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease
Published 2025“…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …”
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1272
Image 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1273
Table 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1274
Table 2_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.docx
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1275
Image 1_Load-bearing aerobic exercise prior to injury moderates systemic immunosuppression response to fracture.jpeg
Published 2025“…Subjects that exercised before fracture had decreased post-fracture circulating immunosuppressive myeloid-derived suppressor cells and pain sensitivity, however there was no significant effect of prehabilitation on bone repair volume, defect bridging rate, or biomechanical properties. …”
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1276
Data Sheet 1_Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research.docx
Published 2024“…</p>Results<p>Acute pain induced significant instability in EGG slow-wave frequency and amplitude, increased tachygastria, and decreased normogastric spectral power, without evidence of sex differences. …”
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1277
<b>Contrasting strategies, shared risk: 12-yr nitrogen addition compromises hydraulic safety in young and mature trees via distinct pathways</b>
Published 2025“…We found that, in young trees, N50 decreased soluble sugars in leaves, twigs, and branches, but increased in roots, suggesting a preferential belowground allocation, whereas N20 responses were limited. …”
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1278
Loss of b-cell K<sub>ATP</sub> reduces Ca<sup>2+</sup> sensitivity of insulin secretion and <i>Trpm5</i> expression
Published 2024“…</a><a href="" target="_blank">Glibenclamide pellet-implanted <i>Trpm5</i> KO mice also exhibited significant glucose intolerance. However, this was not as severe as in WT animals, which suggests that decreased expression of <i>Trpm5</i> may play a small role in the disruption of insulin secretion with K<sub>ATP</sub> loss.…”
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1279
Table 1_Experiences of childhood emotional maltreatment and emotional intelligence in young women.docx
Published 2025“…Regression analysis indicated that emotional neglect was a significant predictor of understanding emotion independent of women’s verbal intelligence, cognitive flexibility, trait anxiety, and depressive symptoms. …”
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1280
Image 2_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff
Published 2025“…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”