بدائل البحث:
significantly impairs » significantly impacts (توسيع البحث), significantly impact (توسيع البحث), significantly improves (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
significantly impairs » significantly impacts (توسيع البحث), significantly impact (توسيع البحث), significantly improves (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
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1341
<b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve...
منشور في 2025"…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …"
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1342
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025
منشور في 2025"…Insulin resistance (IR) can impair MetF, contributing to type 2 diabetes and obesity. …"
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1343
Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr...
منشور في 2024"…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …"
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1344
Lower serum LH level was related to poor embryo quality and adverse pregnancy outcomes in fixed GnRH antagonist protocol with estradiol pretreatment
منشور في 2024"…LH<sub>GI</sub> <3.93 mIU/ml impaired ongoing pregnancy rate and LBR. After adjusting for AMH and AFC, the impacts were not significant. …"
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1345
Table 1_Microplastics in focus: a silent disruptor of liver health- a systematic review.docx
منشور في 2025"…., increased serum cysteine, decreased hepatic cysteine, and disturbed homocysteine metabolism), impair mitochondrial bioenergetics, and lead to significant lipid accumulation after exposures lasting up to 500 h. …"
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1346
DataSheet1_Apoptotic and proliferative processes in the small intestine of rats with type 2 diabetes mellitus after metformin and propionic acid treatment.PDF
منشور في 2024"…</p>Results<p>We observed profound changes in the SI of diabetic rats suggesting the disturbed intestinal homeostasis: impaired mitochondrial ultrastructure, increased cristae volume, and decreased content of proliferative marker Ki67 with almost unchanged proapoptotic caspase-3 and its p17 subunit levels. …"
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1347
Raw data_(Submission ID 247694791)
منشور في 2024"…Deletion of <i>BbNoxB</i> or <i>BbNoxR</i> decreased fungal virulence compared to the WT strain in topical inoculation experiments. …"
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1348
Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i>
منشور في 2025"…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …"
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1349
Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1350
Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx
منشور في 2025"…Cognitive impairment was a significant predictor of non-motor symptoms in their top three tiers [odds ratio [OR]: 3.88 (95% CI: 1.647 to 9.169)]. …"
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1351
Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1352
Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif
منشور في 2024"…Both excessive NET formation and impaired degradation contribute to SLE pathophysiology.…"
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1353
Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (<i>N</i> = 19)
منشور في 2025"…These symptoms can cause severe impairment to a child’s functioning and, if left untreated, have negative long-term consequences. …"
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1354
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
منشور في 2025"…For palbociclib, a CDK4/6 inhibitor, AR activation induced RB1 polyubiquitination and degradation, diminishing RB1 levels—a key downstream target of CDK4/6—and thus impairing palbociclib efficacy. Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …"