Search alternatives:
significantly linked » significantly longer (Expand Search), significantly altered (Expand Search), significantly higher (Expand Search)
linked decrease » marked decrease (Expand Search), linear decrease (Expand Search)
significantly linked » significantly longer (Expand Search), significantly altered (Expand Search), significantly higher (Expand Search)
linked decrease » marked decrease (Expand Search), linear decrease (Expand Search)
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Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents
Published 2025“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”
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Pharmacological induction of mitochondrial dysfunction results in micronuclei and nuclear blebbing.
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Akt3 null animals have reduced Aurora B expression and proliferation and increased apoptosis.
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ROS reduces the expression of Akt3, WDR12 and Aurora B leading to micronuclei.
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Original data (a, b, c, d) and disproportionality analysis results (ROR & IC).
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Characteristics of adolescents with T2D cases reporting ADRs to metformin in FAERS.
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