Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells

Cdc42 is required for EGF-stimulated protrusion and motility in MTLn3 carcinoma cells

Cdc42 plays a central role in regulating the actin cytoskeleton and maintaining cell polarity. Here, we show that Cdc42 is crucial for epidermal growth factor (EGF)- stimulated protrusion in MTLn3 carcinoma cells. When stimulated with EGF, carcinoma cells showed a rapid increase in activated Cdc42 t...

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Bibliographic Details
Main Author: El-Sibai, Mirvat (author)
Other Authors: Nalbant, Peri (author), Pang, Huan (author), Flinn, Rory J. (author), Sarmiento, Corina (author), Macaluso, Frank (author), Cammer, Michael (author), Condeelis, John S. (author), Hahn, Klaus M. (author), Backer, Jonathan M. (author)
Format: article
Published: 2007
Online Access:http://hdl.handle.net/10725/2492
http://dx.doi.org/10.1242/jcs.005942
http://jcs.biologists.org/content/120/19/3465
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http://hdl.handle.net/10725/2492
http://dx.doi.org/10.1242/jcs.005942
http://jcs.biologists.org/content/120/19/3465

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