Isolation and structural elucidation of rosmarinic acid by nuclear magnetic resonance spectroscopy

Lemon balm is a herbal tea known for its therapeutic practice in soothing stomach cramps, indigestion and nausea. One of its chemical components is rosmarinic acid, known for its anti-inflammatory and antiviral activities in treating Herpes simplex. Despite the efforts, recovery and purification of...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Akoury, Elias (author)
التنسيق: article
منشور في: 2019
الوصول للمادة أونلاين:http://hdl.handle.net/10725/10256
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://pdfs.semanticscholar.org/9937/0b9950243b81787909595fc9adade62a69de.pdf
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الوصف
الملخص:Lemon balm is a herbal tea known for its therapeutic practice in soothing stomach cramps, indigestion and nausea. One of its chemical components is rosmarinic acid, known for its anti-inflammatory and antiviral activities in treating Herpes simplex. Despite the efforts, recovery and purification of rosmarinic acid from Lemon balm in high yields has not been entirely successful. Here, we report the aqueous extraction of rosmarinic acid from dried leaves of Lemon balm using Soxhlet distillation after optimizing the conditions with various organic solvents. We have isolated rosmarinic acid under optimum process conditions and high yield (96%) and elucidated its structure by NMR spectroscopy.