Isolation and structural elucidation of rosmarinic acid by nuclear magnetic resonance spectroscopy
Lemon balm is a herbal tea known for its therapeutic practice in soothing stomach cramps, indigestion and nausea. One of its chemical components is rosmarinic acid, known for its anti-inflammatory and antiviral activities in treating Herpes simplex. Despite the efforts, recovery and purification of...
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2019
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| Online Access: | http://hdl.handle.net/10725/10256 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://pdfs.semanticscholar.org/9937/0b9950243b81787909595fc9adade62a69de.pdf |
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| Summary: | Lemon balm is a herbal tea known for its therapeutic practice in soothing stomach cramps, indigestion and nausea. One of its chemical components is rosmarinic acid, known for its anti-inflammatory and antiviral activities in treating Herpes simplex. Despite the efforts, recovery and purification of rosmarinic acid from Lemon balm in high yields has not been entirely successful. Here, we report the aqueous extraction of rosmarinic acid from dried leaves of Lemon balm using Soxhlet distillation after optimizing the conditions with various organic solvents. We have isolated rosmarinic acid under optimum process conditions and high yield (96%) and elucidated its structure by NMR spectroscopy. |
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