Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)

Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)

Anthrax lethal toxin is a two-component toxin consisting of protective antigen (PrAg), the cell binding and translocation domain, and lethal factor (LF), the catalytic domain, which cleaves all mitogen-activated protein/extracellular regulated kinase kinases (MEKs), leading to the inhibition of the...

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Bibliographic Details
Main Author: Al Saneh, Ahmad (author)
Format: masterThesis
Published: 2020
Subjects:
Dissertations, Academic
Cancer > Molecular aspects
Blood > Diseases > Molecular aspects
Mitogen-activated protein kinases
Lebanese American University > Dissertations
Acute myeloid leukemia > Pathogensis
Online Access:http://hdl.handle.net/10725/13448
https://doi.org/10.26756/th.2022.333
http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php
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http://hdl.handle.net/10725/13448
https://doi.org/10.26756/th.2022.333
http://libraries.lau.edu.lb/research/laur/terms-of-use/thesis.php

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