Phospholipase C negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells
The Rho GTPases Rac and Cdc42 play a central role in the regulation of secretory and cytoskeletal responses in antigen-stimulated mast cells. In this study, we examine the kinetics and mechanism of Rac and Cdc42 activation in the rat basophilic leukemia RBL- 2H3 cells. The activation kinetics of bot...
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| Main Author: | El-Sibai, Mirvat (author) |
|---|---|
| Other Authors: | Backer, Jonathan M. (author) |
| Format: | article |
| Published: |
2007
|
| Online Access: | http://hdl.handle.net/10725/2497 http://dx.doi.org/10.1002/eji.200635875 http://onlinelibrary.wiley.com/doi/10.1002/eji.200635875/full |
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