Characterization of the DNA binding and bending HMG domain of the yeast hypoxic repressor Rox1

The yeast Rox1 hypoxic transcriptional repressor protein binds to and bends a specific DNA sequence through an HMG domain located at the N-terminus. To better understand the structure of Rox1 and how it interacts with DNA, 38 missense mutations in the HMG domain were isolated through a combination o...

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Bibliographic Details
Main Author: Khalaf, Roy A. (author)
Other Authors: Deckert, Jutta (author), Hwang, Soo-Myung (author), Zitomer, Richard S. (author)
Format: article
Published: 1999
Online Access:http://hdl.handle.net/10725/3357
http://dx.doi.org/10.1093/nar/27.17.3518
http://nar.oxfordjournals.org/content/27/17/3518.short
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