Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

We have investigated the effects of inhibiting the expression of cofilin to understand its role in protrusion dynamics in metastatic tumor cells, in particular. We show that the suppression of cofilin expression in MTLn3 cells (an apolar randomly moving amoeboid metastatic tumor cell) caused them to...

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Bibliographic Details
Main Author: Sidani, Mazen (author)
Other Authors: Wessels, Deborah (author), Mouneimne, Ghassan (author), Ghosh, Mousumi (author), Goswami, Sumanta (author), Sarmiento, Corina (author), Wang, Weigang (author), Kuhl, Spencer (author), El-Sibai, Mirvat (author), Backer, Jonathan M. (author), Eddy, Robert (author), Soll, David (author), Condeelis, John (author)
Format: article
Published: 2007
Online Access:http://hdl.handle.net/10725/2501
http://dx.doi.org/10.1083/jcb.200707009
http://jcb.rupress.org/content/179/4/777.short
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http://hdl.handle.net/10725/2501
http://dx.doi.org/10.1083/jcb.200707009
http://jcb.rupress.org/content/179/4/777.short

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