Synthesis of new pyrazolo[3,4-d]pyrimidine derivatives and evaluation of their anti-inflammatory and anticancer activities
This study reports the synthesis of two series of new purine bioisosteres comprising a pyrazolo[3,4-d]pyrimidine scaffold linked to piperazine moiety through different amide linkages. The newly synthesized compounds were evaluated for anticancer activity against four cell lines (MDA-MB-231, MCF-7, S...
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| Other Authors: | , , , , , |
| Format: | article |
| Published: |
2017
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| Online Access: | http://hdl.handle.net/10725/5366 http://dx.doi.org/10.1111/cbdd.12929 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://onlinelibrary.wiley.com/doi/10.1111/cbdd.12929/full |
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