Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration
Purpose: MPTP-induced dopaminergic degeneration is an experimental model commonly used to explore Parkinson’s disease. Cerebral drug transport by ABC transporters in MPTP models has never been reported. Methods: We have investigated the transport of bromocriptine through the blood-brain barrier (BBB...
محفوظ في:
| المؤلف الرئيسي: | Milane, Aline (author) |
|---|---|
| مؤلفون آخرون: | Vautier, Sarah (author), Fernandez, Christine (author), Chacun, Helene (author), Lacomble, Luccette (author), Farinotti, Robert (author) |
| التنسيق: | article |
| منشور في: |
2009
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10725/4500 http://dx.doi.org/10.18433/J3B596 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://ejournals.library.ualberta.ca/index.php/JPPS/article/view/1521 |
| الوسوم: |
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مواد مشابهة
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ABCB1 (P-glycoprotein) and blood-brain barrier
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Impact des pompes d'efflux (abcb1 et abcg2) de la barrière hémato-encéphalique sur le passage cérébral du riluzole et de la minocycline
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Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
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Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier
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Interactions between riluzole and ABCG2/BCRP transporter
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