Efficacy of Endoscopic Mucosal Resection for Management of Small Duodenal Neuroendocrine Tumors
Background: Endoscopic mucosal resection (EMR) for small (<20 mm) duodenal neuroendocrine tumors (NETs) remains controversial because of their rarity. Materials and Methods: This is a retrospective cohort study of patients with surgically or endoscopically resected duodenal NETs from 2001 to 2011...
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| Other Authors: | , , , , , , , , |
| Format: | article |
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2015
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| Online Access: | http://hdl.handle.net/10725/4534 http://dx.doi.org/10.1097/SLE.0000000000000192 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://journals.lww.com/surgical-laparoscopy/Abstract/2015/10000/Efficacy_of_Endoscopic_Mucosal_Resection_for.18.aspx |
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| Summary: | Background: Endoscopic mucosal resection (EMR) for small (<20 mm) duodenal neuroendocrine tumors (NETs) remains controversial because of their rarity. Materials and Methods: This is a retrospective cohort study of patients with surgically or endoscopically resected duodenal NETs from 2001 to 2011. The primary outcome is the rate of disease-free status following resection. A secondary outcome is the sensitivity of endoscopic ultrasound (EUS) in determining NET appropriateness for EMR. Results: Thirty patients underwent resection of duodenal NETs (EMR 20, surgery 10). Tumor was present at the margins in 40% of EMR-resected NETs and 10% of surgically resected NETs. Five patients who underwent EMR had residual disease treated with repeat EMR (3) and surgery (2). EUS demonstrated 96% sensitivity in determining lesions limited to the submucosa. Conclusions: EMR for small duodenal NETs can be a safe and effective alternative to surgery in carefully selected patients. EUS is a useful adjunct in determining depth of invasion for duodenal NETs. |
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