Characterization of urokinase plasminogen activator-activated recombinant anthrax toxin for targeted cancer therapy
Anthrax lethal toxin (LeTx), secreted by Bacillus anthracis, consists of protective antigen (PrAg) and lethal factor (LF). Following binding to its ubiquitously expressed cell surface receptors tumor endothelium marker 8 and capillary morphogenesis gene-2, PrAg is cleaved by cell-surface furin and f...
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| Main Author: | Abi-Habib, Ralph J. (author) |
|---|---|
| Other Authors: | Singh, Ravibhushan (author), Duesbery, Nicholas S. (author), Liu, Shihui (author), Bugge, Thomas H. (author), Leppla, Stephen H. (author) |
| Format: | conferenceObject |
| Published: |
2006
|
| Online Access: | http://hdl.handle.net/10725/8053 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php http://cancerres.aacrjournals.org/content/66/8_Supplement/712.4.short |
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