Highly sensitive and selective measurement of underivatized methylmalonic acid in serum and plasma by liquid chromatography-tandem mass spectrometry

Methylmalonic acid (MMA) is a functional biomarker of vitamin B12 deficiency. Measurement of plasma MMA is challenging due to its small molecular weight and hydrophilic nature. Several liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods have been developed for measuring plasma MMA. How...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Yuan, Chao (author)
مؤلفون آخرون: Gabler, Jessica (author), El-Khoury, Joe (author), Spatholt, Regina (author), Wang, Sihe (author)
التنسيق: article
منشور في: 2012
الوصول للمادة أونلاين:http://hdl.handle.net/10725/4025
http://dx.doi.org/10.1007/s00216-012-6099-z7
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://link.springer.com/article/10.1007/s00216-012-6099-z
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