Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts

Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts

The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic lineage, is bone resorption. To resorb bone, OCs form podosomes. These are actin-rich adhesive structures that pattern into rings that drive OC migration and into “sealing-zones” (SZs) that confine the resorption l...

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Bibliographic Details
Main Author: Georgess, Dan (author)
Other Authors: Mazzorana, Marlene (author), Terrado, Jose (author), Delpart, Chrisitne (author), Chamot, Christophe (author), Guasch, Rosa M. (author), Perez-Roger, Ignocia (author), Jurdic, Pierre (author), Machuca-Gayet, Irma (author)
Format: article
Published: 2014
Online Access:http://hdl.handle.net/10725/10338
https://doi.org/10.1091/mbc.e13-07-0363
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.molbiolcell.org/doi/full/10.1091/mbc.e13-07-0363
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http://hdl.handle.net/10725/10338
https://doi.org/10.1091/mbc.e13-07-0363
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.molbiolcell.org/doi/full/10.1091/mbc.e13-07-0363

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