Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts
The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic lineage, is bone resorption. To resorb bone, OCs form podosomes. These are actin-rich adhesive structures that pattern into rings that drive OC migration and into “sealing-zones” (SZs) that confine the resorption l...
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| Format: | article |
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2014
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| Online Access: | http://hdl.handle.net/10725/10338 https://doi.org/10.1091/mbc.e13-07-0363 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.molbiolcell.org/doi/full/10.1091/mbc.e13-07-0363 |
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