DJ-1, a peten inhibitor, is a positive regulator of cancer cell motility. (c2014)
DJ-1 is a 20-KDa protein that was first identified as an oncogene product responsible for a subset of familial Parkinson’s disease; hence its name PARK 7. Previous studies showed that DJ-1 negatively regulated the tumor suppressor gene PTEN expression; thus promoting the phosphorylation of the PI3K/...
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| Format: | masterThesis |
| Published: |
2016
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| Online Access: | http://hdl.handle.net/10725/3258 https://doi.org/10.26756/th.2014.62 |
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