Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier

Unlike primates, rats are resistant to systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity, but direct infusion of MPTP into rat substantia nigra causes specific destruction of dopaminergic neurons. We now demonstrate that rats are resistant to MPTP neurotoxicity even when MPT...

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Bibliographic Details
Main Author: Riachi, Naji J. (author)
Other Authors: Dietrich, W. Dalton (author), Harik, Sami I. (author)
Format: article
Published: 1990
Online Access:http://hdl.handle.net/10725/10436
https://doi.org/10.1016/0006-8993(90)91788-I
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.sciencedirect.com/science/article/pii/000689939091788I
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