Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector
MERTK is an essential component of the signaling network that controls phagocytosis in retinal pigment epithelium (RPE), the loss of which results in photoreceptor degeneration. Previous proof-of-concept studies have demonstrated the efficacy of gene therapy using human MERTK (hMERTK) packaged into...
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| Main Author: | Ghazi, Nicola G. (author) |
|---|---|
| Other Authors: | Abboud, Emad B. (author), Nowilaty, Sawsan R. (author), Alkuraya, Hisham (author), Alhommadi, Abdulrahman (author), Cai, Huimin (author) |
| Format: | article |
| Published: |
2016
|
| Online Access: | http://hdl.handle.net/10725/10798 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://link.springer.com/article/10.1007/s00439-016-1637-y |
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