Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector

MERTK is an essential component of the signaling network that controls phagocytosis in retinal pigment epithelium (RPE), the loss of which results in photoreceptor degeneration. Previous proof-of-concept studies have demonstrated the efficacy of gene therapy using human MERTK (hMERTK) packaged into...

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Bibliographic Details
Main Author: Ghazi, Nicola G. (author)
Other Authors: Abboud, Emad B. (author), Nowilaty, Sawsan R. (author), Alkuraya, Hisham (author), Alhommadi, Abdulrahman (author), Cai, Huimin (author)
Format: article
Published: 2016
Online Access:http://hdl.handle.net/10725/10798
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://link.springer.com/article/10.1007/s00439-016-1637-y
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