β-Sheet core of Tau paired helical filaments revealed by solid-state NMR
One of the hallmarks of Alzheimer’s disease is the self-assembly of the microtubule-associated protein tau into fibers termed “paired helical filaments” (PHFs). However, the structural basis of PHF assembly at atomic detail is largely unknown. Here, we applied solid-state nuclear magnetic resonance...
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2012
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| Online Access: | http://hdl.handle.net/10725/10248 http://dx.doi.org/10.1021/ja305470p http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://pubs.acs.org/doi/abs/10.1021/ja305470p |
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