Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Topotecan, a topoisomerase I inhibitor, is an anticancer drug widely used in the therapy of lung, ovarian, colorectal, and breast adenocarcinoma. Due to the primary dose-limiting toxicity of topotecan, which is myelosuppressive, it is necessary to identify other chemotherapeutic agents that can work...
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| Main Author: | Khalife, Rana (author) |
|---|---|
| Other Authors: | Hodroj, Mohammad Hassan (author), Fakhoury, Rajaa (author), Rizk, Sandra (author) |
| Format: | article |
| Published: |
2016
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| Online Access: | http://hdl.handle.net/10725/8069 http://dx.doi.org/10.1055/s-0035-1558289 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1558289 |
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