Lack of F8 mRNA

Hemophilia A (HA) is caused by partial or total deficiency of F8 protein activity. In a small group, about 1.8% of patients with HA, no mutation is found in the F8 gene. Among this group, we report here on one patient with severe HA in whom no mRNA of the F8 gene was detected. Using 2 common polymor...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: El Maarri, Osman (author)
مؤلفون آخرون: Singer, Heike (author), Klein, Claudia (author), Watzka, Mathias (author), Herbiniaux, Brackmann (author), Schroder, Jorg (author), Graw, Jochen (author), Muller, Clemens (author), Schramm, Wolfgang (author), Schwaab, Rainer (author), Haaf, Thomas (author), Hanfland, Peter (author), Oldenburg, Johannes (author)
التنسيق: article
منشور في: 2006
الوصول للمادة أونلاين:http://hdl.handle.net/10725/6173
https://doi.org/10.1182/blood-2005-09-3702
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://www.bloodjournal.org/content/107/7/2759.short
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