WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

We examined the role of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in cell protrusion in response to epidermal growth factor (EGF), a key regulator in carcinoma cell invasion. We found that WAVE2 knockdown (KD) suppresses lamellipod formation and increa...

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Bibliographic Details
Main Author: Sarmiento, Corina (author)
Other Authors: Wang, Weigang (author), Dovas, Athanassios (author), Yamaguchi, Hideki (author), Sidani, Mazen (author), El-Sibai, Mirvat (author), Desmarais, Vera (author), Holman, Holly A. (author), Kitchen, Susan (author), Backer, Jonathan M. (author), Alberts, Art (author), Condeelis, John (author)
Format: article
Published: 2008
Online Access:http://hdl.handle.net/10725/5198
http://dx.doi.org/110.1083/jcb.200708123
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://jcb.rupress.org/content/180/6/1245/tab-pdf
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