The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. Due to the primary dose-limiting toxicity of topotecan which is myelosuppressio...
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2014
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| Online Access: | http://hdl.handle.net/10725/3524 http://dx.doi.org/10.1016/j.clml.2014.06.049 http://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(14)00204-3/abstract |
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