IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells

Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. Aim: To determine whether ceramide in...

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Bibliographic Details
Main Author: Homaidan, Fadia R. (author)
Other Authors: El-Sabban, Marwan E. (author), Chakroun, Iman (author), El-Sibai, Mirvat (author), Dbaibo, Ghassan S. (author)
Format: article
Published: 2002
Online Access:http://hdl.handle.net/10725/2820
http://dx.doi.org/10.1080/09629350210313
http://www.hindawi.com/journals/mi/2002/467015/abs/
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