The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration
Cell migration involves the localized extension of actinrich protrusions, a process that requires Class I phosphoinositide 3-kinases (PI 3-kinases). Both Rac and Ras have been shown to regulate actin polymerization and activate PI 3-kinase. However, the coordination of Rac, Ras and PI 3-kinase activ...
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| Other Authors: | , , , , , , , , , |
| Format: | article |
| Published: |
2007
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| Online Access: | http://hdl.handle.net/10725/2493 http://dx.doi.org/10.1242/jcs.005298 http://jcs.biologists.org/content/120/17/3138.short |
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