Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells

We previously showed that inhibition of the platelet-derived growth factor receptor (PDGFR) blocks the survival and migration of medulloblastoma cells. Identification of in vitro PDGFR-targeting pharmacologic agents that are suitable for preclinical testing in medulloblastoma models in vivo will be...

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Bibliographic Details
Main Author: Castellino, R.C. (author)
Other Authors: MacDonald, T.J. (author), Abouantoun, Thamara J. (author)
Format: article
Published: 2011
Online Access:http://hdl.handle.net/10725/4421
http://dx.doi.org/10.1007/s11060-010-0259-9
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://link.springer.com/article/10.1007/s11060-010-0259-9
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