Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals

Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals

Rationale: Multiple cyclic nucleotide phosphodiesterases (PDEs) degrade cAMP in cardiomyocytes but the role of PDEs in controlling cAMP signaling during pathological cardiac hypertrophy is poorly defined. Objective: Evaluate the β-adrenergic regulation of cardiac contractility and characterize the c...

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Bibliographic Details
Main Author: Abi-Gerges, Aniella (author)
Other Authors: Richter, Wito (author), Lefebvre, Florence (author), Mateo, Philippe (author), Varin, Audrey (author), Heymes, Chrisrophe (author), Samuel, Jane-Lise (author), Lugnier, Claire (author), Conti, Marco (author), Fischmeister, Rodolphe (author), Vandecasteele, Gregoire (author)
Format: article
Published: 2009
Online Access:http://hdl.handle.net/10725/6358
https://doi.org/10.1161/CIRCRESAHA.109.197947
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.109.197947
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http://hdl.handle.net/10725/6358
https://doi.org/10.1161/CIRCRESAHA.109.197947
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.109.197947

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