Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes

Steady-state activation of cardiac β-adrenergic receptors leads to an intracellular compartmentation of cAMP resulting from localized cyclic nucleotide phosphodiesterase (PDE) activity. To evaluate the time course of the cAMP changes in the different compartments, brief (15 seconds) pulses of isopre...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Leroy, Jerome (author)
مؤلفون آخرون: Abi-Gerges, Aniella (author), Nikolaev, Viacheslav O. (author), Richter, Wito (author), Lecheme, Patrick (author), Mazet, Jean-Luc (author), Conti, Marco (author), Fischmeister, Rodolphe (author), Vandecasteele, Gregoire (author)
التنسيق: article
منشور في: 2008
الوصول للمادة أونلاين:http://hdl.handle.net/10725/6356
https://doi.org/10.1161/CIRCRESAHA.107.167817
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.107.167817
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