Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes

Steady-state activation of cardiac β-adrenergic receptors leads to an intracellular compartmentation of cAMP resulting from localized cyclic nucleotide phosphodiesterase (PDE) activity. To evaluate the time course of the cAMP changes in the different compartments, brief (15 seconds) pulses of isopre...

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Bibliographic Details
Main Author:	Leroy, Jerome (author)
Other Authors:	Abi-Gerges, Aniella (author), Nikolaev, Viacheslav O. (author), Richter, Wito (author), Lecheme, Patrick (author), Mazet, Jean-Luc (author), Conti, Marco (author), Fischmeister, Rodolphe (author), Vandecasteele, Gregoire (author)
Format:	article
Published:	2008
Online Access:	http://hdl.handle.net/10725/6356 https://doi.org/10.1161/CIRCRESAHA.107.167817 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.107.167817
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Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes

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