Guanine glycation repair by DJ-1/Park7 and its bacterial homologs

Guanine glycation repair by DJ-1/Park7 and its bacterial homologs

DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA glycation, is quantitatively as important as oxidative damage. DNA glycation is associated with increased mutation frequency, DNA strand breaks, and cytotoxicity. However, in contrast to guanine oxidation repair,...

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Bibliographic Details
Main Author: Richarme, Gilbert (author)
Other Authors: Liu, Cailing (author), Mihoub, Mouadh (author), Abdallah, Jad (author), Leger, Thibaut (author), Joly, Nicolas (author), Liebart, Jean-Claude (author), Jurkun, Ula V. (author)
Format: article
Published: 2017
Online Access:http://hdl.handle.net/10725/10677
https://doi.org/10.1126/science.aag1095
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://science.sciencemag.org/content/357/6347/208/tab-article-info
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http://hdl.handle.net/10725/10677
https://doi.org/10.1126/science.aag1095
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
https://science.sciencemag.org/content/357/6347/208/tab-article-info

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