BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin
Anthrax lethal toxin, composed of protective antigen and lethal factor, was tested for cytotoxicity to human melanoma cell lines and normal human cells. Eleven of 18 melanoma cell lines were sensitive to anthrax lethal toxin (IC50 < 400 pmol/L) and 10 of these 11 sensitive cell lines carried the...
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| Other Authors: | , , , |
| Format: | article |
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2005
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| Online Access: | http://hdl.handle.net/10725/2731 http://dx.doi.org/10.1158/1535-7163.MCT-05-0145 http://mct.aacrjournals.org/content/4/9/1303.short |
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