A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types

Urokinase plasminogen activator (uPA) is a tumor-specific protease highly expressed in several types of solid tumors and rarely present on normal cells under physiologic conditions. Due to its high expression on metastatic tumors, several different strategies have been used to target the urokinase s...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Abi-Habib, Ralph J. (author)
مؤلفون آخرون: Singh, Ravibhushan (author), Liu, Shihui (author), Bugge, Thomas (author), Leppla, Stephen H. (author), Frankel, Arthur (author)
التنسيق: article
منشور في: 2006
الوصول للمادة أونلاين:http://hdl.handle.net/10725/2744
http://dx.doi.org/ 10.1158/1535-7163.MCT-06-0315
http://mct.aacrjournals.org/content/5/10/2556.short
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