Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer

Overexpression of the human epidermal growth factor receptor (HER) family has been implicated in cancer because of its participation in signaling pathways regulating cellular proliferation, differentiation, motility, and survival. In this work, we exploited the extracellular binding property of tras...

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Bibliographic Details
Main Author: Sampath, Lakshmi (author)
Other Authors: Kwon, Sunkuk (author), Ke, Shi (author), Wang, Wei (author), Schiff, Rachel (author), Mawad, Michel E. (author), Sevick-Muraca, Eva M. (author)
Format: article
Published: 2007
Online Access:http://hdl.handle.net/10725/10992
http://dx.doi.org/10.2967/jnumed.107.042234
http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php
http://jnm.snmjournals.org/content/48/9/1501.short
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