Functional Characterization of Novel <i>MC4R </i>Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
<p dir="ltr">The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The <i>MC4R</i> gene plays a central role in leptin–melanocortin signaling,...
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2023
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