Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes

<div><p>The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin resistance and vascular complications in diabetes. Cons...

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Main Author: Naila Rabbani (291722) (author)
Other Authors: Mingzhan Xue (3607649) (author), Paul J. Thornalley (291723) (author)
Published: 2022
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