Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
<div><p>The recent discovery of the glucose-induced stabilization of hexokinase-2 (HK2) to proteolysis in cell dysfunction in model hyperglycemia has revealed a likely key initiating factor contributing to the development of insulin resistance and vascular complications in diabetes. Cons...
محفوظ في:
| المؤلف الرئيسي: | Naila Rabbani (291722) (author) |
|---|---|
| مؤلفون آخرون: | Mingzhan Xue (3607649) (author), Paul J. Thornalley (291723) (author) |
| منشور في: |
2022
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| الموضوعات: | |
| الوسوم: |
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مواد مشابهة
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Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complications
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